Platelet adhesiveness and aggregability

Platelet adhesiveness.

Platelet Adhesiveness

By MURRAY WEINER, M.D., KURT ZELTMACHER, M.D., CARL REICH, M.D., AND SHEPARD SHAPIRO, M.D. I N 1941, Helen Wright’ described a method for estimating the adhesive quality of platelets. Confirmation of the original findings by Spooner and Meyer’ established the procedure as a means of distinguishing this property of platelets. It is the purpose of the present report to evaluate the usefulness of ...

Platelet Aggregability And Fibrinolytic Activity

s Background:Sexual dimorphism in coronary artery disease (CAD) mortality is attributed to the cardioprotective effects of estrogen.This is reinforced by the observation that incidence of myocardial infarction is higher in menstrual phase, corresponding with low estrogen levels, in people who are predisposed to CAD due to the presence of modifiable risk factors. Cyclical variability of estrogen...

Epidemiological characteristics of platelet aggregability.

The epidemiological characteristics of platelet aggregability were established in 958 participants in the Northwick Park Heart Study. The main analyses were based on the dose of adenosine diphosphate at which primary aggregation occurred at half its maximum velocity. Aggregability increased with age in both sexes, was greater in whites than blacks (particularly among men), and tended to decreas...

Platelet adhesiveness after blood donation.

Platelet adhesiveness to glass was measured in healthy blood donors at the time of and eight days after donating 500 ml of blood. By a whole blood method a highly significant increase was found whereas by a method using platelet-rich plasma with added adenosine diphosphate there was only a slightly significant increase. The discrepancy suggested that changes in the red cell population might inf...